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Should I take enteric-coated aspirin to protect my stomach? Enteric-coated aspirin is designed to resist dissolving and being absorbed in the stomach. The purported goal is to prevent stomach ulcers and bleeding that can sometimes occur with aspirin use. When it comes to preventing a heart attack or stroke , the purpose of taking low-dose aspirin is to help prevent the development of harmful — or deadly — artery-blocking blood clots.
However, with enteric-coated aspirin, research indicates that bloodstream absorption may be delayed and reduced, compared to regular aspirin absorption. Regular aspirin is quickly dissolved and absorbed in the stomach.
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